| 세션명 | 의료용 고분자 부문위원회 (I) |
|---|---|
| 발표장 | 제2회장 |
| 논문코드 | 1L2-5 |
| 발표일 | 2021-10-21 |
| 발표시간 | 16:00-16:25 |
| 논문제목 | The power of graphene on induction of spontaneous myogenesis |
| 발표자 | 한동욱 |
| 발표자 소속 | 부산대학교 |
| 저자 | 한동욱†, 박기동1, 박경민2 |
| 소속 | 부산대학교; 1아주대학교; 2인천대학교 |
| 논문초록 | 3D Bioprinting has attracted considerable attention for producing 3D engineered cellular microenvironments that replicate complex and sophisticated native ECM as well as the spatiotemporal gradients of numerous physicochemical and biological cues. Although various hydrogel-based bioinks have been reported, the development of advanced bioinks that can reproduce the complexity of ECM accurately and mimic the intrinsic property of laden cells is still a challenge. Herein, I present 3D printable bioinks composed of phenol-rich gelatin (GHPA) and graphene oxide (GO) which can form a hydrogel network in situ by a dual enzyme-mediated cross-linking reaction. The in situ curable GO/GHPA hydrogel can be utilized successfully as 3D-printable bioinks to provide suitable cellular microenvironments with facilitated myogenic differentiation of C2C12 skeletal myoblasts. Overall, it is suggested that functional bioinks may be useful in muscle tissue engineering and regeneration. |
THE POLYMER SOCIETY OF KOREA